In collaboration with Proteus Digital Health, the CBC is studying an ingestible sensor solution that can be implanted into medications for a population of USC heart failure patients. These sensors are networked and can communicate with data clouds, allowing for easy monitoring of medication adherence by physicians and patient family members to assist in treatment. Patients are also able to access and manage their medications, steps, activity, rest, heart rate, blood pressure and weight through the Proteus mobile app. The study will analyze the ability of the Proteus platform to be utilized as a chronic disease management tool for patients needing to adhere to multiple medications. Patients in the study will be taking two to three heart failure management medications and we will validate sensor transmission as well as the applicability of the platform for hospital to home transition care.